tag:blogger.com,1999:blog-10000891.comments2024-02-21T19:56:57.057-08:00California Stem Cell ReportDavid Jensenhttp://www.blogger.com/profile/00077329461962729362noreply@blogger.comBlogger1283125tag:blogger.com,1999:blog-10000891.post-41859416737734374612021-03-18T09:47:41.488-07:002021-03-18T09:47:41.488-07:00It's time to subscribe -- free! -- to the Cali...It's time to subscribe -- free! -- to the California Stem Cell Report, which has moved to a new platform. <br /><br />Don't miss news and information concerning critical developments at the $12 billion California stem cell agency. It is the leading, independent and reliable source for all that happens at the California Institute for Regenerative Medicine (CIRM). <br /><br />With more than 3 million page views and more than 5,000 items during the last 16 years, the Report's readers range from researchers throughout California to across the nation. Not to mention policymakers and entrepreneurs in the burgeoning stem cell field. "Indispensable" is how the Los Angeles Times described the California Stem Cell Report.<br /><br />You can subscribe on the blog's new platform while reading the latest CIRM news. Please do it today. Go to the "new" California Stem Cell Report here. https://david293.substack.com/California Stem Cell Report -- David Jensenhttps://www.blogger.com/profile/10594203393373241511noreply@blogger.comtag:blogger.com,1999:blog-10000891.post-46252972511161584072021-01-12T09:01:12.336-08:002021-01-12T09:01:12.336-08:00I'm sure that Larry will do an excellent job o...I'm sure that Larry will do an excellent job on the Board and he brings a unique depth of knowledge on stem cell research. However, along the lines of what Aaron said as quoted in the piece, at the very least the appointment presents some challenges of perception of the agency.<br />-- Paul KnoepflerPaulhttps://www.blogger.com/profile/07977566113013157487noreply@blogger.comtag:blogger.com,1999:blog-10000891.post-7036015521825682062020-12-17T05:06:05.434-08:002020-12-17T05:06:05.434-08:00I bought David Jensen's book, and recommend it...I bought David Jensen's book, and recommend it. He and I often disagree on CIRM (I think it is great, he thinks it needs work) but Jensen is a reporter and his writing is an unparalleled source for background information.diverdonreedhttps://www.blogger.com/profile/15770005979754357175noreply@blogger.comtag:blogger.com,1999:blog-10000891.post-89829087715583825142020-11-19T20:00:43.300-08:002020-11-19T20:00:43.300-08:00To paraphrase the great John Updike, McCormack and...To paraphrase the great John Updike, McCormack and indeed many in Cirm leadership are "masters of the imagined sleight." They gobble great amounts of cash, feel sort of justified but also sheepish about it and have in response become very sensitive.jon Shestackhttps://www.blogger.com/profile/03544357515225881698noreply@blogger.comtag:blogger.com,1999:blog-10000891.post-53191503779885300172020-11-19T16:32:48.930-08:002020-11-19T16:32:48.930-08:00Why are they so sensitive? It is what it is. I a...Why are they so sensitive? It is what it is. I attended one once- the CIRM people didn't take it very seriously- not my observation, a comment from a member of that body.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-10000891.post-21666093615176538022020-11-17T13:40:58.570-08:002020-11-17T13:40:58.570-08:00David- I wouldn't call this a debate, but it w...David- I wouldn't call this a debate, but it was good to be in a news article with Zach Hall and Arlene Chiu, two people who I greatly admire. I haven't kept my opinions of CIRM Part One's flaws a secret. My work benefited greatly from CIRM funding ($22 million as PI), so luckily my personal opinions didn't affect my success as a scientist. Stem cell scientists should not be afraid to participate in policy development in CIRM Part Two- there are opportunities for new cases of the problems that Zach Hall pointed out, and it's in our own interest to give CIRM feedback as they evolve. Jeanne Loringhttps://en.wikipedia.org/wiki/Jeanne_Loringnoreply@blogger.comtag:blogger.com,1999:blog-10000891.post-1361334690873810822020-11-14T10:50:11.681-08:002020-11-14T10:50:11.681-08:00I was initially against this proposition, thinking...I was initially against this proposition, thinking it was too much money to throw towards something the previous 3 billion dollars didn't deliver on. But then someone pointed out that the Democratic politicians in this state had planted several money trees behind the State Capitol. So I guess money is no longer need be part of the calculation when deciding propositions.Sean Bearlyhttps://www.blogger.com/profile/05737434687164437894noreply@blogger.comtag:blogger.com,1999:blog-10000891.post-44239552026502788282020-11-09T10:18:17.867-08:002020-11-09T10:18:17.867-08:00Re the 55 percent question, only 50 percent, plus ...Re the 55 percent question, only 50 percent, plus one additional vote is needed.California Stem Cell Report -- David Jensenhttps://www.blogger.com/profile/10594203393373241511noreply@blogger.comtag:blogger.com,1999:blog-10000891.post-4387537161245723332020-11-09T01:01:46.710-08:002020-11-09T01:01:46.710-08:00Stem cell research started with transgenic and kno...Stem cell research started with transgenic and knockout mice decades ago. Some of what is out in the public domain is considered "prior art" for the purposes of patenting. Very much an issue in trying to commercialize a treatment as the development for the technology for use in people will run out the patent clock with flimsily constructed utility patents. If this passed (?) and nothing actionable comes out in terms of clinical treatment with what is nowadays priced at around $1B/drug to develop, it will slam the door shut on any other direct to public fund raising of this type. Lobbyists will ask to see where those 8 approved drugs are after almost 2 decades on injecting money into the system. Furthermore given that $3B did not yield any drugs or diagnostics while a pandemic is raging is a very poor public image and likely to hurt science endeavors such as these especially when there are other means of funding. Investors will look overseas for the research. It's perhaps wise to see how much of the $5B is slated for clinical development and what sort of partnerships have been developed for that. Academics do not have the expertise nor the wherewithal to do the scale-up required for clinical development. Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-10000891.post-60896161035412130952020-11-04T09:14:57.472-08:002020-11-04T09:14:57.472-08:00I thought it requires 55% approval David?I thought it requires 55% approval David?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-10000891.post-14519464913415986462020-10-25T18:25:46.939-07:002020-10-25T18:25:46.939-07:00John- good to hear from you!John- good to hear from you!Jeanne Loringnoreply@blogger.comtag:blogger.com,1999:blog-10000891.post-14721971915194678992020-10-25T16:01:25.083-07:002020-10-25T16:01:25.083-07:001. David Jensen’s book is well worth reading.
2. V...1. David Jensen’s book is well worth reading.<br />2. Vote NO on Prop 14.<br /> — John M. Simpson, former Stem Cell Project Director at Consumer Watchdog, now retired.JMShttps://www.blogger.com/profile/08308570006368632871noreply@blogger.comtag:blogger.com,1999:blog-10000891.post-76372493013236028612020-10-25T16:01:08.199-07:002020-10-25T16:01:08.199-07:001. David Jensen’s book is well worth reading.
2. V...1. David Jensen’s book is well worth reading.<br />2. Vote NO on Prop 14.<br /> — John M. Simpson, former Stem Cell Project Director at Consumer Watchdog, now retired.JMShttps://www.blogger.com/profile/08308570006368632871noreply@blogger.comtag:blogger.com,1999:blog-10000891.post-22774925482051347732020-10-13T20:10:28.808-07:002020-10-13T20:10:28.808-07:00Hi Ben- did you have a grant for hESCs before 2001...Hi Ben- did you have a grant for hESCs before 2001?JFLhttps://www.blogger.com/profile/05098609536551279483noreply@blogger.comtag:blogger.com,1999:blog-10000891.post-39766197048019164132020-10-13T11:37:59.651-07:002020-10-13T11:37:59.651-07:00Loring is incorrect in asserting that Bush was fir...Loring is incorrect in asserting that Bush was first to authorize federal stem cell guidelines. Clinton did in August of 2000: https://www.wired.com/2000/08/clinton-oks-stem-cell-researchBen Kaplanhttps://www.blogger.com/profile/00291534001006307700noreply@blogger.comtag:blogger.com,1999:blog-10000891.post-58369546002236674922020-10-10T11:47:35.072-07:002020-10-10T11:47:35.072-07:00I would argue that CIRM has served its greatest pu...I would argue that CIRM has served its greatest purpose. I think I used the CIRM funding I received wisely, and when CIRM wouldn't fund me for clinical development of a cell replacement therapy for Parkinson's disease, I raised foundation and venture capital funding and founded a company to follow through. That was exactly the intention of Prop 71- not to hold our hands but to to give us the power to follow through by ourselves.Jeanne Loringhttps://en.wikipedia.org/wiki/Jeanne_Loringnoreply@blogger.comtag:blogger.com,1999:blog-10000891.post-8475344695544063732020-10-08T17:22:21.610-07:002020-10-08T17:22:21.610-07:00Thank you for an informative article.People need t...Thank you for an informative article.People need to clearly understand the proposition. I support stem cell research.Eurocathttps://www.blogger.com/profile/00438727084334057011noreply@blogger.comtag:blogger.com,1999:blog-10000891.post-25485454364305318212020-10-01T18:50:38.510-07:002020-10-01T18:50:38.510-07:00Excellent reporting by veteran journalist David Je...Excellent reporting by veteran journalist David Jensen on the latest editorial. I'll look forward (hopefully tomorrow) on what DJ thinks is the impact, or lack of impact, this and other newspaper editorials have on the outcome of this and other ballot measures (if ever).Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-10000891.post-44858146981223902762020-09-10T09:51:34.176-07:002020-09-10T09:51:34.176-07:00Thank you, David, for saving me the trouble of rea...Thank you, David, for saving me the trouble of reading and rereading the proposition. It is considerably different from Prop. 71. JFLhttps://www.blogger.com/profile/05098609536551279483noreply@blogger.comtag:blogger.com,1999:blog-10000891.post-75402573434260705822020-09-02T15:43:25.411-07:002020-09-02T15:43:25.411-07:00Appreciate your extensive analysis of this Proposi...Appreciate your extensive analysis of this Proposition - seems almost like a Christmas tree bill in Congress in the old days, something for everyone. I don't personally think this is a good way to run a RR, but without opposition, I think the proposition will pass. Tedhttps://www.blogger.com/profile/03512676576747999898noreply@blogger.comtag:blogger.com,1999:blog-10000891.post-7589078633674556152020-07-14T10:21:42.036-07:002020-07-14T10:21:42.036-07:00Let me get this straight. Celularity declines to s...Let me get this straight. Celularity declines to say where in California their testing will be done. Meanwhile, the agency knows but it is deferring to the company? What idiots! Thank god you are there to keep them transparent. Again, what idiots!!Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-10000891.post-16370271175913024422020-06-26T06:51:16.214-07:002020-06-26T06:51:16.214-07:00I think it more honest to list the amount requeste...I think it more honest to list the amount requested, 5.5 Billion then add, itemized, the interest. To many do not understand it has to be paid back WITH Interest. I do not think a few thousand jobs should depend on the voters, if this work is important enough, a it may be, the Feds are more in a position, this does California very little plus how much has gone to China, what kind of security do they run?Hrwolfehttps://www.blogger.com/profile/01576980430342449095noreply@blogger.comtag:blogger.com,1999:blog-10000891.post-30701305818195358202020-06-15T06:51:42.652-07:002020-06-15T06:51:42.652-07:00Newsom obviously has been busy. But if he is going...Newsom obviously has been busy. But if he is going to endorse the measure, it would be better to wait until later this summer or early fall, when voters' attention will be more focused on California measures on the November 3 ballot. Plus he actually may have qualms about increased spending long term because of the need to pay the interest on the $5.5 billion in state borrowing. It was one thing to endorse this in 2004. The situation involving stem cell research has changed significantly. It could change again before the election. David Jensenhttps://www.blogger.com/profile/00077329461962729362noreply@blogger.comtag:blogger.com,1999:blog-10000891.post-37435518246075239372020-06-12T12:12:05.428-07:002020-06-12T12:12:05.428-07:00I suspect that the budget cuts have made it diffic...I suspect that the budget cuts have made it difficult for him to support anything outside the normal business of the state.JFLhttps://www.blogger.com/profile/05098609536551279483noreply@blogger.comtag:blogger.com,1999:blog-10000891.post-11565047277488331982020-06-11T08:28:50.254-07:002020-06-11T08:28:50.254-07:00Any idea why Gavin is being mum? Do you think he i...Any idea why Gavin is being mum? Do you think he is ashamed of his previous support?Anonymousnoreply@blogger.com