Stem Cell Video Flap: A Look at the California Firm Backing the 'Docu-Series'

A California physician deeply enmeshed in the national ruckus over a controversial, stem cell video has -- according to his web site -- "achieved world-renown as a pioneer in the area of stem cell research."

He is Mark Berman, one of the co-founders of Cell Surgical Network (CSN), which partly financed the lengthy, online video, "Healthcare Revolution." At least 12 scientists, other experts and institutions reacted with shock last week when they became fully aware of its approach and financing. They asked that they be removed from the film.

Mark Berman,  photo from Berman web site

One researcher called the video an "infomercial." Another said she was placed with "charlatans and thieves."

Berman's firm has been sued by the Food and Drug Administration as part of an effort to curb untested and potentially dangerous stem cell treatments. The number of dubious stem cell clinics has grown sharply in recent years. Estimates are that 1,000 exist nationally, with the highest percentage in California.

On Sunday he emailed the irate scientists and asked them to reconsider their requests for removal. None apparently did. 

What follows is a brief look at Berman's history and that of his firm, which has offices in Beverly Hills and Rancho Mirage, Ca., and about 100 affiliates nationwide and more abroad. 

But first, the text of his response to questions from the California Stem Cell Report about the video and its financing. The "docu-series" was produced by Bobby and Sara Sheehan and their firm, Working Pictures.

"I met Bobby and Sara when they came to interview me at my office for another project they were working on a couple years ago. We were commenting on all the amazing work being done in the field of cell therapy and stem cell research, yet all the surrounding controversy. A lot of this was due to people putting random unmatched cells into patients for a whole host of conditions and not adequately tracking the follow up. We thought it would be really important to show some of the world’s greatest minds, who have devoted, in some cases, decades to advancing this field, and highlight all the great work that’s currently being done to advance healthcare.

"I’m not sure what the entire series cost. We were just a tiny part of this film. Bobby and Sara spent over a year flying around the world to get this project done. they worked completely independently from us. Neither I, nor anyone in CSN, paid anyone that was interviewed or promised them compensation. We have zero financial interest in Working Pictures, nor do they have any financial interest in CSN. 

"This whole project is about educating people on the work being done to advance healthcare and we think it’s important that the word gets out."

Berman's website says he has practiced cosmetic surgery since 1983 and started his stem cell practice in 2010.  He is co-founder of Cell Surgical Network and the California Stem Cell Treatment Center. 

Erin Allday of the San Francisco Chronicle reported last year: 

"For more than three decades, Berman’s focus was breast augmentations and face-lifts. He invented a pocket-like device that can be implanted into the breast to produce better-looking, safer results from augmentation procedures. He calls it his “Sistine Chapel.”

With his business partner, Rancho Mirage (Riverside County) urologist Elliot Lander, Berman has built the largest chain of stem cell clinics in the country. Their Cell Surgical Network has more than a hundred affiliates in 33 states — including 38 clinics in California alone — selling treatments they claim will fix everything from knee pain to symptoms of multiple sclerosis.But over the past eight years, Berman has reached far past his specialty into a realm of highly sophisticated, still-nascent medicine. He’s become one of the country’s most outspoken and notorious providers of so-called consumer stem cell therapies: using human stem cells to treat a wide variety of ailments despite little or no scientific proof that they work.

“As a cosmetic surgeon, it’s kind of a joke that I’m at the center of this universe,” Berman said in an interview last fall (2017). “But I’m kind of ground zero.”

"Seven months later, his words became darkly prophetic: In May, Berman and his partner were targeted by the U.S. Food and Drug Administration. The FDA requested an injunction that, if approved by a federal judge, would stop them from selling stem cell therapies. 

"The FDA issued a similar request against a separate operation in Florida, U.S. Stem Cell Clinic.

"Their clinics, though, are just some among several hundred that have popped up across the country in recent years. They are renegade outposts operating with little legitimacy and oversight at the frontier of what is otherwise a highly promising field of medicine."

Here is a short list of other sources of information involving Berman, his treatments and  enterprises: 

• Stem cell scientist Paul Knoepfler of UC Davis has written extensively about Berman and Cell Surgical Network, going back to 2013 when Knoepfler published this Q&A.
• Vox recently carried an overview of unregulated stem cell treatments, including Berman's firm. 
• A Washington Post story about the 2018 FDA filing against Cell Surgical Network.

Stem Cell Video Flap: A Look at the Firm that Produced the "Docu-Series"

Bobby Sheehan discusses his personal and professional background in this YouTube clip.

Who are Bobby and Sara Sheehan, not to mention Working Pictures? 

It is a question that arises from their controversial "docu-series" that raised a ruckus this week in the small world of stem cell science.

Their online video, "Healthcare Revolution," was an unpleasant surprise for at least 12 scientists and other experts who learned only a few days ago they were appearing in the production. All of them asked to be removed.

They believed that they had been misled about how interviews that they had given many months ago were going to be used. 

They objected to sharing an electronic platform with dubious enterprises that are current targets of the federal government's actions to shut down dangerous and unproven stem cell treatments. 

Executives of those firms also appeared in the video in a manner that was considered a case of "false equivalency."

Earllier this week, the California Stem Cell Report queried Sara Sheehan about the video and their links to a California stem cell firm, Cell Surgical Network, with 100 national affiliates that the Food and Drug Administration is suing. 

The full text of her response runs below. But first a little background drawn from the Internet.

Sara Sheehan is executive producer for Working Pictures, according to its web site.  Her husband, Bobby, is producer, director, writer and cameraman. Their web site says Bobby had a "nomadic and slightly feral" upbringing. It also said, 

Sara Sheehan
 Working Pictures photo

"Collectively, they have produced well over a hundred hours of content in the form of online and conventional TV series, documentaries, and narrative films. Bobby has directed and lensed over 300 commercials…and they have produced three talented children."

The Sheehans are also associated with another enterprise called "Mortal," which deals with death and spiritual awareness. 

The California Stem Cell Report asked Sara Sheehan about the cost of the stem cell docu-series, which was partly financed by Cell Surgical Network, and any other financial ties with that firm.  Here is the verbatim text of her reply.

"I appreciate your asking us to provide additional information and I have answered your questions below: 

"We set out to produce a documentary series about the very complex regenerative medicine landscape. There is a lot of information out there and consumers are faced with a daunting amount of opposing opinions and concerns. We felt that by showing the entire landscape - including advances in research that will be providing hope to patients years down the line, the fact that many consumers are going overseas for treatments, the legislation that has been enacted in this country, patients who have gotten treatments in this country and other countries and their outcomes, and the lawsuits- we would educate the consumers who would see this and allow them to make the best decisions for themselves and their loved ones. 

"We looked for financing for the series, which took a year to make. We had investors, Drs. Berman and Landers (of Cell Surgical Network) were part of that team. Never did they ask to see edits, to control the content or interfere with the story in any way. That was the deal. The rest of the costs we bootstrapped ourselves: our investors did not pay us for our time and we covered many costs ourselves. We are not connected in any other way to Cell Surgical Network or any other regenerative medicine provider, nor do we stand to benefit financially from any procedures or products being marketed. We have no family members connected to Cell Surgical Network or any other regenerative medicine providers. The bottom line is that we are filmmakers who attempted to outline what is clearly a heated and emotionally charged environment. Ironically, Cell Surgical Network is featured most prominently in an episode entitled The Lawsuits, outlining the cases against US Stem Cell and Cell Surgical Network. We had updated that episode to reflect the decision against US Stem Cell. 

"We never paid anyone to be interviewed. In fact I have NEVER paid anyone to be interviewed for this project or any other project.

"After a year of interviewing and editing as many and as varied voices as possible, the resulting series is 12 episodes long. We organized the information by subject and feel we had a comprehensive product that provided a good, basic overview of the field that included many opposing points of view. There is a tremendous amount of information contained in the series that we felt showed as much of the landscape as we were allowed to capture.

"Unfortunately, a number of people expressed concern about being included in the project and we immediately responded that we would honor their wishes to be removed."

Stem Cell Video Flap: World Stem Cell Summit Withdraws from 'Docu-Series'

The chairman of the World Stem Cell Summit today said that he has asked that his organization be removed from any mention in a controversial online video about stem cell therapies.

Bernard Siegel, chair of the Summit, said,

"My organization's stand on the 'Bad Actors' is clear from the numerous posting and interviews. We support the FDA in enforcement actions and condemn the actions of the purveyors of bogus treatments, false and misleading claims."

Siegel's remarks came in response to questions this morning from the California Stem Cell Report. He said that he also asked that his interview be withdrawn from the 10-part "docu-series." Some of interviews that appear in the video were done at one of the Summit conferences. 

A number of researchers and others have also asked that they be removed the video, "Healthcare Revolution," because of its ties to a California stem cell firm, Cell Surgical Network (CSN), that is the target of federal regulators. The CEO of the California stem cell agency is also listed as an interviewee in the video. 

Siegel said that the World Stem Cell Summit has no financial connection to CSN, which partially financed the video. He also said the Summit had no financial ties to Working Pictures, the firm that produced the video or its principals, Bobby and Sara Sheehan.

The Food and Drug Administration (FDA) is seeking to halt treatments provided by CSN, which has about 100 affiliates nationwide and more overseas.  CSN has offices in Beverly Hills and Rancho Mirage, Ca. (For more information on the FDA action, see here and also here.

Here is the full text of Siegel's response to the California Stem Cell Report.

"The Sheehans appeared to be, by all accounts, legitimate filmmakers with a long track record of quality productions. They did film several interviews at the World Stem Cell Summit for their documentary. The Summit team was unaware of any links the production had with Cell Surgical Network. We were surprised last week when the trailer was released and saw how the series was being framed promotionally.

"The Summit, or any other organization that I am affiliated with, certainly has no connection to the Cell Surgical Network financial or otherwise. Upon learning that CSN funded the production, I withdrew my own interview from the project and requested the removal of any reference to my organization.

"We have no financial ties to the Sheehans or their production company. I have spoken to Sara and Bobby Sheehan who instantly agreed to remove any individual who sought to remove his or her interview from the series. They have proven themselves totally cooperative to date in that regard. They appear to be caught in the middle of a war, unfortunately lacking the depth of understanding.

"My organization's stand on the 'Bad Actors' is clear from the numerous posting and interviews. We support the the FDA in enforcement actions and condemn the actions of the purveyors of bogus treatments, false and misleading claims."